Skin Cancer Staging
Staging of basal cell or squamous cell carcinoma
| Stage
0: |
Carcinoma in
situ that is confined to the epidermis - the top layer of the skin (see Skin Anatomy).
Squamous cell carcinoma in situ - also known as Bowen's disease - is the first stage of
squamous cell skin cancer. |
| Stage
1: |
Small tumor that is less than 2 centimeters in size and
has not spread to the lymph nodes or other organs. |
| Stage
2: |
Tumor that
is larger than 2 centimeters, but has not spread to the lymph nodes or other organs.
|
| Stage
3: |
Tumor that
has metastasized (spread) to the tissues under the skin (muscle, bone, or cartilage)
and/or to the regional (nearby) lymph nodes. |
| Stage
4: |
Tumor of any
size that has metastasized (spread) to distant organs such as the lungs or brain. |
Saging for Melamona
The AJCC staging system is based on three sets of criteria: how thick the tumor is (T),
the extent to which it has spread to the lymph nodes (N), and the extent to which it has
metastasized to other parts of the body (M). The AJCC staging system is outlined below,
with the TNM parameters and corresponding Clark's level in parentheses. The TNM levels are
explained following the outline of the staging system. The AJCC and the Clark's level
stages do not always correspond, and when they don't, the AJCC system should always take
precedence.
| Stage 0 |
This is
melanoma in situ, meaning the cancer is in the epidermis and has not begun to spread yet.
(Clark's level I) |
| Stage IA
|
Localized melanoma that
is less than 0.75 mm (Clark's level II: the tumor has spread to the upper dermis; T1N0M0).
|
| Stage IB
|
Localized melanoma that
is thicker than 0.75 mm but less than 1.5 mm (Clark's level III: the tumor involves most
of the upper dermis); T2N0M0). |
| Stage
IIA |
Localized melanoma that
is thicker than 1.5 mm but less than 4 mm (Clark's level IV: the tumor has spread to the
lower dermis; T3N0M0). |
| Stage
IIB |
Localized melanoma that
is greater than 4 mm (Clark's level V: the tumor has spread beneath the dermis; T4N0M0). |
| Stage
III |
The melanoma has spread
to nearby lymph nodes or less than 5 in-transit metastases are found. An in-transit
metastasis is metastasis that is located between the primary tumor and the closest lymph
node region. It results from melanoma cells getting trapped in the lymphatic channels (any
T, N1M0). |
| Stage IV
|
The tumor has
metastasized to other parts of the body (any T, any N, M1 or M2). |
TNM levels
Thickness of the primary tumor (T):
| T1:
|
The
tumor is 0.75 mm or less in thickenss and invades the upper dermis. |
| T2: |
The tumor
is more than 0.75 mm but not more than 1.5 mm in thickness and/or begins to invade the
lower dermis. |
| T3: |
The tumor
is more than 1.5 mm but not more than 4 mm in thickness and/or invades the lower dermis. |
| T3a: |
The tumor
is more than 1.5 mm but not more than 3 mm in thickness. |
| T3b: |
The tumor
is more than 3 mm but not more than 4 mm in thickness. |
| T4: |
The tumor
is more than 4 mm in thickness and/or invades the subcutaneous tissue (the tissue beneath the
skin) and/or satellites within 2 cm of the primary tumor. |
| T4a: |
The tumor
is more than 4 mm in thickness and/or invades the subcutaneous tissue. |
| T4b: |
The tumor
satellites within 2 cm of the primary tumor. |
Involvement of The Regional Lymph Nodes (N)
| NX: |
The
regional lymph nodes cannot be assessed.
|
| N0: |
There is no
regional lymph node metastasis. |
| N1: |
Metastasis
is 3 cm or less in greatest dimension in any regional lymph node(s). |
| N2: |
Metastasis
is more than 3 cm in greatest dimension in any regional lymph node(s) and/or there is
in-transit metastasis. An in-transit metastasis is one that is located between the primary
tumor and the closest lymph node region. It results from melanoma cells getting trapped in
the lymphatic channels. |
| N2a: |
Metastasis
is more than 3 cm in greatest dimension in any regional lymph node. |
| N2b: |
There is
in-transit metastasis. |
| N2c: |
Both N2a
and N2b. |
Extent of Distant Metastasis (M)
| MX: |
Distant
metastasis cannot be assessed. |
| M0: |
There is no
distant metastasis. |
| M1: |
Distant
metastasis is present. |
| M1a: |
Metastasis
is in the skin or subcutaneous tissue or lymph node(s) beyond the regional lymph nodes. |
| M1b: |
Metastasis
occurs in other parts of the body.
|
|